Corneal Physician Bulletin: Cataract Surgery in Infancy Raises Risk of Glaucoma

   The risk of glaucoma-related adverse events increases the longer the follow-up of children who undergo unilateral cataract extraction during infancy, and the risk has nothing to do with IOL implantation, reports a recent study in JAMA Ophthalmology.1|
    Specifically, the Infant Aphakic Treatment Study showed that the risk of glaucoma and glaucoma plus the glaucoma suspect diagnosis at 10 years increased to 22% and 40%, respectively, sans difference among treatment groups (primary intraocular lens vs aphakia). 
    The multicenter randomized clinical trial was comprised of 114 infants (ages 1 to 6 months at surgery) who had unilateral congenital cataract removal. Information regarding long-term glaucoma-related status and outcomes was amassed when these children were around 10 years old and then assessed from March 30, 2019 to August 6, 2019.
    The study’s researchers say the findings “support the need for lifelong surveillance for glaucoma and glaucoma-related events following cataract removal in infancy.”


1. JAMA Ophthalmol. doi:10.1001/jamaophthalmol.2020.5664